In autosomal recessive inheritance, if two carrier parents have a child affected, what is the probability the next child will be unaffected?

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Multiple Choice

In autosomal recessive inheritance, if two carrier parents have a child affected, what is the probability the next child will be unaffected?

Explanation:
In autosomal recessive inheritance, two carrier parents (Aa x Aa) produce offspring with genotypes: AA (1/4), Aa (1/2), and aa (1/4). The disease occurs only with aa, so the chance of an unaffected child (either AA or Aa) is 1/4 + 1/2 = 3/4, or 75%. Each pregnancy is independent, so the probability for the next child being unaffected remains 75%.

In autosomal recessive inheritance, two carrier parents (Aa x Aa) produce offspring with genotypes: AA (1/4), Aa (1/2), and aa (1/4). The disease occurs only with aa, so the chance of an unaffected child (either AA or Aa) is 1/4 + 1/2 = 3/4, or 75%. Each pregnancy is independent, so the probability for the next child being unaffected remains 75%.

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